rs12316890 (CCDC91): Pregnancy loss in nulliparas

Key takeaways

  • The rs12316890 SNP is linked to pregnancy loss in nulliparous women.
  • Effect size reported is 4.51 p=6e-6.
  • Only this variant is associated with the trait.

Key takeaways The rs12316890 SNP is linked to pregnancy loss in nulliparous women. The effect size reported is 4.51 p=6e-6. Only this variant is associated with the trait.

What the research says This variant is associated with Pregnancy loss in nulliparas risk/effect allele T PMID 38714721

Reported associations Pregnancy loss The rs12316890 variant is linked to pregnancy loss in nulliparas risk allele T reported effect size 4.51 p=6e-6 PMID 38714721

Evidence quality The GWAS used about 7 thousand individuals and reported a p-value of 6e-6 indicating strong association. No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs12316890 mean?

It is a genetic change in CCDC91 that has been linked to pregnancy loss for women who have never given birth.

Is this variant related to nulliparity?

Yes the variant appears in studies associated with pregnancy loss in nulliparous women.

What is the effect size of rs12316890?

The reported effect size is 4.51 p=6e-6.