rs11895588 (LRP1B): no known association
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Key takeaways
- rs11895588 is a variant in LRP1B
- No association with congenital heart defects reported
- Evidence limited by small sample size
Key takeaways rs11895588 is a variant in LRP1B No association with congenital heart defects reported Evidence limited by small sample size
What the research says The provided studies do not report any association for rs11895588 [PMID 28468790].
Reported associations No direct trait association reported for this variant [PMID 28468790].
Evidence quality The study used about 300 to 400 participants and found a genome-wide significant association for rs72820264 with left ventricular obstructive tract defect (p=2.1×10-8) but the sample size limits power to detect small effects [PMID 28468790].
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does the rs11895588 variant mean?
It is a single nucleotide change in the LRP1B gene.
Is rs11895588 linked to heart defects?
No association has been found between this variant and congenital heart defects based on available studies.
Why is evidence limited for rs11895588?
The study that examined related variants used a small sample size which limits the ability to detect subtle effects.