rs117462359 OPCML linked to oligodendroglioma

Key takeaways

  • This SNP is linked to a brain tumor called oligodendroglioma.
  • The effect size is 5.92 with p=1e-6.
  • It was studied in about 9000 people.

Key takeaways This SNP is linked to a brain tumor called oligodendroglioma. The effect size is 5.92 with p=1e-6. It was studied in about 9000 people.

What the research says The rs117462359 variant in the OPCML gene is associated with oligodendroglioma a brain tumor PMID 36810956. The reported effect size is 5.92 p=1e-6 in about 9 thousand individuals.

Reported associations Oligodendroglioma (brain tumor) the variant raises risk with a reported effect size of 5.92 p=1e-6 [PMID 36810956].

Evidence quality The supplied studies include one GWAS catalog association in about 9 thousand individuals reporting an effect size of 5.92 p=1e-6 for oligodendroglioma [PMID 36810956]. No replication data are provided.

No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs117462359 mean?

It is a single nucleotide change in the OPCML gene that has been linked to oligodendroglioma.

Is this variant dangerous?

Being associated with oligodendroglioma means it may increase risk but it does not guarantee disease.

What is the effect size of rs117462359?

The reported effect size is 5.92 p=1e-6 in about 9 thousand individuals.