rs117402698 - OPCML anxiety gaming link

Key takeaways

  • This SNP is linked to anxiety when playing computer games.
  • The effect size is moderate with p=7e-12.
  • It is a common risk signal not a rare disease allele.

Key takeaways This SNP is linked to anxiety when playing computer games, the effect size is moderate and the study involved nearly half a million people. The GWAS catalog reports an association between this variant and higher anxiety during gaming sessions with p=7e-12. It is not a rare disease allele but a common risk signal.

What the research says The GWAS catalog reports that rs117402698 is associated with anxiety severity when playing computer games, with a reported effect size of 1.99 and p=7e-12 PMID 34877740

Reported associations Anxiety severity x playing computer games interaction This variant is associated with higher anxiety when playing computer games a reported effect size of 1.99 and p=7e-12 PMID 34877740

Evidence quality The GWAS used about 488 thousand individuals, reporting an effect size of 1.99 and p=7e-12 PMID 34877740 The association is not replicated in other studies.

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs117402698 mean?

rs117402698 is a genetic variant at the OPCML locus that has been associated with higher anxiety when playing computer games.

Is this a rare disease gene?

No, rs117402698 is not linked to a rare disease; it is a common risk signal for anxiety in gaming contexts.

Can I change my behavior based on this result?

The study does not recommend any lifestyle changes; it only describes an association between the variant and higher anxiety during gaming.