rs117202086 (LINC02763): keratoconus risk
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Key takeaways
- rs117202086 is linked to keratoconus
- risk allele G increases likelihood of condition
- effect size 3.69 p=2e-11
Key takeaways rs117202086 is linked to keratoconus risk allele G increases likelihood of condition effect size 3.69 p=2e-11
What the research says The GWAS Catalog reports that the rs117202086 variant is associated with keratoconus, with the G allele increasing risk PMID 39024449. The reported effect size is 3.69 and p=2e-11 in about 573 thousand individuals [PMID 39024449].
Reported associations Keratoconus The rs117202086 G allele is associated with increased risk of keratoconus, reported effect size 3.69 p=2e-11 in about 573 thousand individuals [PMID 39024449].
Evidence quality The association is based on a genome-wide association study of about 573 thousand individuals with the G allele conferring higher risk for keratoconus, p=2e-11. No further replication studies are provided in this catalog entry.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs117202086 mean?
It is a genetic variant at the LINC02763 locus that has been linked to keratoconus, with the G allele associated with higher risk.
Is this variant related to eye health?
Yes it is associated with keratoconus which affects the cornea and can cause vision problems.