TENM2 rs116675619 Pilocytic astrocytoma link

Key takeaways

  • This variant is linked to Pilocytic astrocytoma
  • Effect size reported is 4.56 p=7e-6 in about 7000 individuals
  • Sample size supports a strong association

Key takeaways

  • This variant is linked to Pilocytic astrocytoma
  • Effect size reported is 4.56 p=7e-6 in about 7000 individuals
  • Sample size supports a strong association

What the research says This variant is associated with Pilocytic astrocytoma [PMID 36810956]. The effect size reported is 4.56 p=7e-6 in about 7 thousand individuals.

Reported associations Pilocytic astrocytoma: This variant increases risk of Pilocytic astrocytoma with a reported effect size of 4.56 p=7e-6 [PMID 36810956].

Evidence quality The GWAS catalog association is based on data from about 7 thousand individuals and reports an effect size of 4.56 with a p-value of 7e-6 indicating a strong statistical association. The variant appears in the catalog as rs116675619 TENM2 [PMID 36810956]. No other studies were provided that discuss this locus directly.

No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs116675619 mean?

rs116675619 is a TENM2 variant that has been associated with Pilocytic astrocytoma in a large genetic study.

Is this variant dangerous?

The association is strong but the variant itself does not cause disease; it is linked to a cancer condition.

Can I test for rs116675619?

Yes you can order a DNA test that includes this TENM2 region if you want to see your own genotype.