rs116264057 - TENM2 linked to high-grade astrocytoma
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Key takeaways
- This variant is linked to high-grade astrocytoma a rare brain cancer
- The effect size reported is 3.87 with p=5e-6 in about 7 thousand people
Key takeaways
- This variant is linked to high-grade astrocytoma a rare brain cancer
- The effect size reported is 3.87 with p=5e-6 in about 7 thousand people
What the research says This variant rs116264057 - TENM2 is associated with high-grade astrocytoma a rare brain cancer. The reported effect size is 3.87 and p=5e-6 based on about 7 thousand individuals [PMID 36810956].
Reported associations
- Astrocytoma (high-grade) the variant increases risk with an effect size of 3.87 p=5e-6 in about 7 thousand individuals [PMID 36810956].
Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog association [PMID 36810956]. The evidence is limited to one case series with small sample size.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs116264057 mean?
It is a change in the TENM2 gene that has been linked to high-grade astrocytoma according to one study.
Is this variant common?
The study examined about 7 thousand individuals and found the association but it is not described as common or rare.
Can I get a test for this?
There is no specific test for rs116264057; standard brain cancer screening may detect related changes.