rs116176238 (LINC01122): glioblastoma association
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Key takeaways
- This variant is linked to glioblastoma
- The reported effect size is 7.47 p=1e-7 in about 9 thousand individuals
- It is a rare association with this brain cancer
Key takeaways
- This variant is linked to glioblastoma
- The reported effect size is 7.47 p=1e-7 in about 9 thousand individuals
- It is a rare association with this brain cancer
What the research says The GWAS catalog reports that rs116176238 is associated with glioblastoma, a brain cancer, with an effect size of 7.47 and p=1e-7 in about 9 thousand individuals PMID 36810956
Reported associations Glioblastoma: linked to this variant, reported effect size 7.47 p=1e-7 in about 9 thousand individuals [PMID 36810956].
Evidence quality The evidence comes from a single GWAS catalog association with a sample of about 9 thousand individuals and a very low p-value of 1e-7. The effect size is reported as 7.47. No other studies are provided in the catalog for this variant, so replication has not been demonstrated.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs116176238 mean?
It is a genetic variant at the LINC01122 locus that has been linked to glioblastoma in large population studies.
Is this variant common?
The variant appears in about 9 thousand individuals and has a very low p-value indicating strong association but it is not necessarily common.
Can I test for this variant?
Testing for rs116176238 may be possible through clinical labs that offer genetic risk panels, though it is not widely used.