NAV2 rs11605275 linked to Peripheral arterial disease
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Key takeaways
- This variant is linked to Peripheral arterial disease in a traffic-related air pollution interaction
- The effect size reported is 6.16 with p=9e-6 based on about 2 thousand individuals
- The association is from a single GWAS catalog entry
Key takeaways
- This variant is linked to Peripheral arterial disease in a traffic-related air pollution interaction [PMID 27082954]
- The effect size reported is 6.16 with p=9e-6 based on about 2 thousand individuals [PMID 27082954]
What the research says This variant rs11605275 in NAV2 is associated with Peripheral arterial disease when combined with traffic-related air pollution exposure. The reported effect size is 6.16 p=9e-6 in about 2 thousand individuals [PMID 27082954].
Reported associations
- Peripheral arterial disease: the variant is associated with this condition in a traffic-related air pollution interaction with an effect size of 6.16 p=9e-6 [PMID 27082954]
Evidence quality The supplied study reports an association between rs11605275 and Peripheral arterial disease in about 2 thousand individuals with a reported effect size of 6.16 p=9e-6 [PMID 27082954]. The evidence is limited to this single GWAS catalog entry.
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs11605275 mean?
rs11605275 is a genetic variant in the NAV2 gene that has been associated with Peripheral arterial disease when combined with traffic-related air pollution exposure.
Is this variant harmful?
The study shows an association between the variant and Peripheral arterial disease but does not indicate causation or individual risk.
Can I change my lifestyle to avoid this effect?
No specific lifestyle advice is provided for this variant as no lifestyle considerations are on file.