rs115434241 - RBFOX1: ulcerative colitis link

Key takeaways

  • This SNP is linked to ulcerative colitis
  • The effect size reported is 11.66 with p=3e-6
  • Risk allele A is associated

Key takeaways

  • This SNP is linked to ulcerative colitis
  • The effect size reported is 11.66 with p=3e-6
  • Risk allele A is associated

What the research says This variant rs115434241 in RBFOX1 is associated with ulcerative colitis risk allele A with a reported effect size of 11.66 and p=3e-6 in about 5 thousand individuals [PMID 41661118].

Reported associations

  • Ulcerative colitis: This variant is associated with ulcerative colitis risk allele A with a reported effect size of 11.66 and p=3e-6 in about 5 thousand individuals [PMID 41661118].

Evidence quality The GWAS Catalog association for rs115434241 is based on a study of about 5 thousand individuals reporting an effect size of 11.66 and p=3e-6 [PMID 41661118]. No other studies are provided so replication status is unknown.

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs115434241 mean?

rs115434241 is a genetic variant in the RBFOX1 gene that has been linked to ulcerative colitis risk allele A with a small effect size.

Is this SNP related to other diseases?

The GWAS study only reports an association with ulcerative colitis and no evidence for other disease links.

Can I change my diet because of this variant?

No lifestyle considerations are available for this variant so dietary changes are not recommended based on the data.