rs115110965 - RBFOX1: sTREM-2 levels
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Key takeaways
- rs115110965 is linked to higher cerebrospinal fluid sTREM-2 levels
- the effect size is very small and highly significant
- this association was found in a genome-wide association study of about 1000 participants
Key takeaways
- rs115110965 is linked to higher cerebrospinal fluid sTREM-2 levels
- the effect size is very small and highly significant
- this association was found in a genome-wide association study of about 1000 participants
What the research says This variant is associated with cerebrospinal fluid sTREM-2 levels, reported effect size 15744.73, p=4e-12, in about 1 thousand individuals PMID 31708768
Reported associations Cerebral spinal fluid sTREM-2 levels: this variant is associated with higher levels, reported effect size 15744.73, p=4e-12, in about 1 thousand individuals PMID 31708768
Evidence quality The GWAS catalog association was reported from a study of approximately one thousand individuals, yielding an effect size of 15744.73 and p=4e-12. This is the only source for this variant; there are no conflicting findings PMID 31708768
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs115110965 do?
It is associated with higher levels of cerebrospinal fluid sTREM-2, a protein that may be involved in brain health.
Is this variant linked to disease?
The study shows an association but no evidence it causes disease.
Can I change my diet based on this?
There is no dietary recommendation tied to this SNP; lifestyle considerations are not available for it.