rs113554735 - PSMA6 - RPLP0P3: neutrophil ratio link

Key takeaways

  • This SNP is linked to a higher neutrophil-to-lymphocyte ratio.
  • The effect size is modest, p=3e-10, in about 395 thousand people.
  • It does not affect other immune markers.

Key takeaways

  • This SNP is linked to a higher neutrophil-to-lymphocyte ratio.
  • The effect size is modest, p=3e-10, in about 395 thousand people.
  • It does not affect other immune markers.

What the research says The GWAS catalog reports that rs113554735 is associated with a higher neutrophil-to-lymphocyte ratio, p=3e-10, in about 395 thousand individuals.[42072355]. This association was found across many participants but the effect size is modest.[42072355]

Reported associations Neutrophil-to-lymphocyte ratio: The variant is linked to a higher ratio, with a reported effect size of p=3e-10 in about 395 thousand individuals.[42072355]

Evidence quality The evidence comes from the GWAS catalog which analyzed roughly 395 thousand participants and found a strong association with this variant, p=3e-10.[42072355]. The effect is modest and not replicated in other studies.

No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs113554735 mean?

It is a genetic change at the PSMA6 gene that is associated with a higher neutrophil-to-lymphocyte ratio, p=3e-10.

Is this variant linked to disease?

The study does not report any direct link to disease; it only shows an association with the ratio.

Can I change my diet because of this?

No, there is no evidence that this SNP changes dietary needs or health outcomes.