rs113516553 (ATP2B1-AS1): linked to heart rate changes in heart failure
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Key takeaways
- rs113516553 is linked to heart rate changes in heart failure patients
- effect size reported as 10.02 p=6e-6
- sample size around 1 thousand
Key takeaways rs113516553 is linked to heart rate changes in heart failure patients effect size reported as 10.02 p=6e-6 sample size around 1 thousand
What the research says This variant is associated with heart rate in heart failure with reduced ejection fraction PMID 31113495 The reported effect size is 10.02, p=6e-6, based on about 1 thousand individuals PMID 31113495
Reported associations
- Heart rate in heart failure with reduced ejection fraction - this variant is linked to changes in heart rate, reported effect size 10.02 p=6e-6 in about 1 thousand individuals PMID 31113495
Evidence quality The GWAS Catalog association is based on a single study of about 1 thousand individuals reporting an effect size of 10.02 and p=6e-6 for heart rate in heart failure with reduced ejection fraction [PMID 31113495]. No replication studies are listed, so the evidence remains preliminary. No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs113516553 do?
It is a genetic variant that has been associated with changes in heart rate among people who have heart failure.
Is this variant linked to heart failure?
Yes, the study found an association between the rs113516553 SNP and heart rate in individuals diagnosed with heart failure.
How strong is the effect of rs113516553 on heart rate?
The reported effect size is 10.02 with a p-value of 6e-6, indicating a statistically significant association in about 1 thousand participants.