TENM2 rs112964125 and glioblastoma

Key takeaways

  • rs112964125 TENM2 is linked to glioblastoma
  • The variant shows a strong association in about 7 thousand individuals
  • Effect size reported is 19.02 p=3e-7

Key takeaways

  • This variant is linked to glioblastoma with a reported effect size of 19.02 p=3e-7 in about 7 thousand individuals.
  • The association is based on GWAS Catalog data.

What the research says This variant rs112964125 TENM2 is associated with glioblastoma a rare brain cancer. The reported effect size is 19.02 p=3e-7 in about 7 thousand individuals [PMID 36810956].

Reported associations Glioblastoma: This variant is linked to glioblastoma a rare brain cancer with a reported effect size of 19.02 p=3e-7 in about 7 thousand individuals [PMID 36810956].

Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog data. No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs112964125 mean?

It is a single nucleotide change in the TENM2 gene that has been linked to glioblastoma based on GWAS data.

Is this variant common or rare?

The variant appears in about 7 thousand individuals which suggests it is not extremely rare but present at a moderate frequency.

Can I test for this variant?

Testing for rs112964125 can be done through standard genetic testing services that include TENM2 analysis.