rs112896149 - RBFOX1 prostate cancer association

Key takeaways

  • Prostate cancer association with effect size 1.87 p=5e-6 in about 1 thousand individuals
  • The G allele is linked to higher risk of prostate cancer
  • This variant is part of RBFOX1 gene

Key takeaways

  • Prostate cancer association with effect size 1.87 p=5e-6 in about 1 thousand individuals
  • The G allele is linked to higher risk of prostate cancer
  • This variant is part of RBFOX1 gene

What the research says This variant rs112896149 in RBFOX1 is associated with prostate cancer a reported effect size of 1.87 p=5e-6 in about 1 thousand individuals risk allele G [PMID 29356057].

Reported associations

  • Prostate cancer The variant increases the risk of prostate cancer by a reported effect size of 1.87 p=5e-6 in about 1 thousand individuals [PMID 29356057]

Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog association [PMID 29356057]. No lifestyle considerations on file for this variant.

Lifestyle context

Concrete actions anchored to the cited research. We do not prescribe, we describe.

Screening

  • prostate cancer screening Moderate

    rs112896149 G allele is associated with increased prostate cancer risk (OR 1.87)

    starting at age 40, discuss screening frequency with your physician

Frequently asked questions

What does the rs112896149 variant do?

It is a genetic change in the RBFOX1 gene that has been linked to prostate cancer risk.

Is this variant common?

Yes it appears in about 1 thousand individuals with an effect size of 1.87 p=5e-6.

Can I get a test for this?

Testing is not recommended as the evidence does not support clinical use.