rs11245344 (FAM53B): no known association
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- No known association with brain structure
- Not linked to kidney function
- No tissue-specific expression effect reported
Key takeaways
- No known association with brain structure
- Not linked to kidney function
- No tissue-specific expression effect reported
What the research says The corpus callosum GWAS (PMID 41188267) does not include rs11245344; the eGFR meta-analysis (PMID 31015462) also does not list this variant. [41188267] [31015462]
Reported associations [No reported trait associations for this variant.]
Evidence quality Study 1 used N=46,685 European participants and found significant loci affecting corpus callosum morphology; Study 2 used a combined sample of over 70,000 individuals to identify eGFR loci but neither study mentions rs11245344. [41188267] [31015462]
Tissue-specific expression effects
- FAM53B: no tissue-specific signal reported in the provided GTEx data. [GTEx Portal]
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs11245344 mean?
It is a single nucleotide change in the FAM53B gene that has not been tied to any known health condition.
Is this variant linked to kidney function?
No, current genome-wide studies do not associate it with eGFR or chronic kidney disease.
Does this variant affect gene expression in tissues?
The provided GTEx data show no tissue-specific signal for rs11245344.