rs112328442 CSMD1 type 2 diabetes association

Key takeaways

  • The rs112328442 C allele is linked to type 2 diabetes.
  • Effect size reported is 1.84 with p=9e-6.
  • Study involved about 4 thousand individuals.
  • No lifestyle considerations are known for this variant.

Key takeaways The rs112328442 C allele is linked to type 2 diabetes. Effect size reported is 1.84 with p=9e-6. Study involved about 4 thousand individuals. No lifestyle considerations are known for this variant.

What the research says The rs112328442 C allele of CSMD1 is associated with type 2 diabetes a reported effect size of 1.84 p=9e-6 in about 4 thousand individuals PMID 31049640.

Reported associations Type 2 diabetes The variant is associated with type 2 diabetes a reported effect size of 1.84 p=9e-6 in about 4 thousand individuals PMID 31049640.

Evidence quality The GWAS Catalog association is based on a study of about 4 thousand individuals with the variant allele C and type 2 diabetes reported effect size 1.84 p=9e-6 [PMID 31049640]. The evidence is strong but limited to this single cohort.

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What does the rs112328442 C allele mean?

It is a single nucleotide change in the CSMD1 gene that has been associated with type 2 diabetes.

Is this variant common or rare?

The study reports it as a common variant with an effect size of 1.84 p=9e-6.

Can I change my diet to avoid the risk?

There are no lifestyle recommendations for this variant; no evidence suggests dietary changes will affect diabetes risk.