rs111372745 PTPRN2 ulcerative colitis SNP
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This SNP is linked to ulcerative colitis.
- The risk allele C increases the odds of disease.
- Effect size reported is 3.61 with p-value 3e-6.
- Study used Tractor method on African ancestry.
Key takeaways
- This SNP is linked to ulcerative colitis.
- The risk allele C increases the odds of disease.
- Effect size reported is 3.61 with p-value 3e-6.
- Study used Tractor method on African ancestry.
What the research says The GWAS catalog shows association between rs111372745 and ulcerative colitis. The risk allele C is associated with higher disease risk. Effect size 3.61 p=3e-6 in about 5000 individuals [41661118].
Reported associations
- Ulcerative colitis the variant increases disease risk with a reported effect size of 3.61 p=3e-6 in about 5 thousand individuals [41661118].
Evidence quality The evidence comes from a single GWAS catalog association with ulcerative colitis using the Tractor method on African ancestry individuals. Sample size about 5000 participants. The effect is significant with p=3e-6. No replication data provided [41661118].
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs111372745 mean?
rs111372745 is a single nucleotide change in the PTPRN2 gene that has been linked to ulcerative colitis.
Is this variant related to other diseases?
The study only reports an association with ulcerative colitis and no evidence for other conditions.
Can I test for this SNP?
Testing is possible through genetic testing services but the clinical significance remains limited to research findings.