rs111371067 (ATP2B1-AS1): heart rate in heart failure
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Key takeaways
- rs111371067 is linked to heart rate in heart failure patients
- the effect size reported is 10.02 p=6e-6
- sample size was about 1000 individuals
Key takeaways rs111371067 is linked to heart rate in heart failure patients the effect size reported is 10.02 p=6e-6 sample size was about 1000 individuals
What the research says This variant is associated with heart rate in heart failure with reduced ejection fraction, reported effect size 10.02 p=6e-6 in about 1 thousand individuals [PMID 31113495]. The association was found in a genome-wide association study of heart failure patients [PMID 31113495].
Reported associations Heart rate in heart failure with reduced ejection fraction is associated with this variant a reported effect size of 10.02 p=6e-6 [PMID 31113495].
Evidence quality The evidence comes from a single GWAS catalog association with a sample size of about 1000 individuals and a p-value of 6e-6 indicating strong statistical significance [PMID 31113495]. The reported effect size is 10.02.
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Frequently asked questions
What does rs111371067 mean?
rs111371067 is a single nucleotide change in the ATP2B1 gene that has been associated with higher heart rate in people who have heart failure.
Is this variant linked to heart failure?
Yes it has been found associated with heart rate changes in patients with heart failure based on a GWAS study.
Can I change my heart rate by taking supplements?
There is no evidence that supplements affect the effect of rs111371067 on heart rate.