rs11065756 - CCDC63

Magnitude 2.0 · 1 study on file

Reported associations

• New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population - Unknown journal (n.d.) · Unknown authors · PubMed 29632305

  ABSTRACT: To identify novel loci for susceptibility to MetS, we conducted genome-wide association and exome wide association studies consisting of a discovery stage cohort (KARE, 1946 cases and 6427 controls), and a replication stage cohort (HEXA, 430 cases and 3,264 controls). For finding genetic variants for MetS, with its components, we performed multivariate analysis for common and rare associations, using a standard logistic regression analysis for MetS. From the discovery and replication GWA studies, we confirmed 21 genome-wide signals significantly associated with MetS. Of these 21, four were previously unreported to associate with any MetS components: rs765547 near LPL; rs3782889 in MYL2; and rs11065756 and rs10849915 in CCDC63. Using exome chip variants, gene-based analysis of rar

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