rs10976993 PTPRD CXCL11 association

Key takeaways

  • This variant is linked to higher CXCL11 levels with a reported effect size of 4.65 p=3e-6 in about 318 people
  • The association is based on a genome-wide association study catalog entry
  • No rare disease effects are known for this common variant

Key takeaways

  • This variant is linked to higher CXCL11 levels with a reported effect size of 4.65 p=3e-6 in about 318 people
  • The association is based on a genome-wide association study catalog entry
  • No rare disease effects are known for this common variant

What the research says This variant rs10976993 at PTPRD is associated with higher CXCL11 levels reported effect size 4.65 p=3e-6 in about 318 individuals [PMID 38326779]. The study uses a genome-wide association catalog to link the SNP to this protein level.

Reported associations CXCL11 This variant is linked to higher CXCL11 levels with a reported effect size of 4.65 p=3e-6 in about 318 individuals [PMID 38326779].

Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog entry PMID 38326779.

No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs10976993 mean?

rs10976993 is a single nucleotide change in the PTPRD gene that has been linked to higher CXCL11 levels.

Is this variant dangerous?

The study shows only a modest association with CXCL11 and no evidence of disease risk.

Can I test for this variant?

Yes it is listed in public databases like the GWAS Catalog but testing requires a DNA sample analysis.