rs10968750 - LINGO2 Alzheimer's risk
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- rs10968750 is a genetic variant linked to Alzheimer's disease
- The reported effect size is 2.63 with p=2e-6 in about 4 thousand individuals
- Only the T allele is associated and it increases risk
- This association is seen only in hypertension-negative participants
Key takeaways
- rs10968750 is a genetic variant linked to Alzheimer's disease
- The reported effect size is 2.63 with p=2e-6 in about 4 thousand individuals
- Only the T allele is associated and it increases risk
- This association is seen only in hypertension-negative participants
What the research says rs10968750 is associated with Alzheimer's disease in hypertension-negative individuals PMID 31055733 and the effect size is 2.63, p=2e-6 PMID 31055733.
Reported associations
- Alzheimer's disease: rs10968750 increases risk with a reported effect size of 2.63, p=2e-6 PMID 31055733
Evidence quality the GWAS includes about 4 thousand individuals and reports a significant association with Alzheimer's disease in hypertension-negative participants PMID 31055733. no other studies are provided; the evidence is limited to this single report.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs10968750 mean?
It is a genetic variant in the LINGO2 gene that has been linked to Alzheimer's disease in people who are not hypertensive, with an effect size of 2.63 and p=2e-6.
Is this variant common?
The GWAS includes about 4 thousand participants and reports only the T allele as associated; it is not a rare disease-causing variant but a modestly significant association.
Can I change my risk?
This study does not provide any information on how to modify lifestyle or treatment based on this variant.