rs1084490 - PDE4B: Substance Use Disorder Link
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- rs1084490 is linked to substance use disorder
- the T allele has a reported effect size of 6.56 p=6e-11
- this association was found in about 1.5 million people
Key takeaways rs1084490 is linked to substance use disorder the T allele has a reported effect size of 6.56 p=6e-11 this association was found in about 1.5 million people
What the research says rs1084490 is linked to substance use disorder PMID 41057643 The risk allele T has a reported effect size of 6.56 and p-value 6e-11 PMID 41057643
Reported associations Substance use disorder the risk allele T is associated with substance use disorder with a reported effect size of 6.56 p=6e-11 PMID 41057643
Evidence quality The evidence comes from the GWAS Catalog association in about 1.5 million individuals PMID 41057643 and shows a reported effect size of 6.56 p=6e-11 for the T allele. No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs1084490 mean?
rs1084490 is a common genetic variant in the PDE4B gene that has been associated with substance use disorder.
Is this variant linked to health problems?
Yes it is linked to substance use disorder but no other health issues are reported.
Can I change my risk?
The evidence does not suggest any actionable changes for individuals based on this finding.