rs10825269 PCDH15 Irritable bowel syndrome
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to Irritable bowel syndrome with an effect size of 1.55 and p=5e-6 in about 1 thousand individuals.
- The association comes from GWAS Catalog data.
- The risk allele is T.
Key takeaways
- This variant is linked to Irritable bowel syndrome with an effect size of 1.55 and p=5e-6 in about 1 thousand individuals.
- The association comes from GWAS Catalog data.
- The risk allele is T.
What the research says This variant rs10825269 PCDH15 is associated with Irritable bowel syndrome PMID 24797007. The effect size reported is 1.55 and the p-value is 5e-6 in a sample of about 1 thousand individuals.
Reported associations
- Irritable bowel syndrome this variant increases risk with an effect size of 1.55 and p=5e-6 PMID 24797007.
Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog data. No lifestyle considerations on file for this variant.
Frequently asked questions
What does the PCDH15 gene do?
PCDH15 is a protein that helps regulate calcium channels in nerve cells and may influence gut function.
Is rs10825269 linked to Irritable bowel syndrome?
Yes the variant is associated with irritable bowel syndrome according to GWAS data.
Can this variant cause other health issues?
The evidence only links it to gut symptoms and no other conditions are reported.