rs10790768 (CNTN5): Candida-induced protein regulation
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Key takeaways
- The rs10790768 variant is linked to protein changes during Candida infection.
- It affects how the body handles fungal infections.
- No direct health risk reported.
Key takeaways
- The rs10790768 variant is linked to protein changes during Candida infection.
- It affects how the body handles fungal infections.
- No direct health risk reported.
What the research says The study reports pQTLs and eQTLs in Candida-induced blood, showing that only a fraction of protein variants correlate with gene expression. The region includes genes such as MMP-1 and AMZ1 which were implicated in the network [36865558].
Reported associations
- Candida-induced secretory protein abundance: the variant is associated with increased protein levels in response to infection, reported effect size 0.07 p=1e-9 in about 300 people [36865558].
Evidence quality The supplied studies involve meta-analysis of 30,931 samples across two cohorts, reporting pQTLs with modest replication (only ~35% overlap with eQTLs). The evidence is preliminary and not specific to rs10790768 [36865558].
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs10790768 mean?
It is a single-nucleotide change in the CNTN5 gene that has been associated with protein changes during Candida infection.
Is this variant linked to disease?
The evidence shows only modest effects on protein levels and no clear health risk.
Can I test for this variant?
Testing is possible through DNA analysis services but the clinical significance remains unclear.