rs10773076 (RFLNA): Height Association

Key takeaways

• rs10773076 is located near the RFLNA gene
• Associated with height variation in large population studies
• The C allele is linked to the observed effect
• Research relies on genome-wide association data

What the research says Large-scale genetic studies have identified rs10773076 as a common variant near the RFLNA gene that correlates with differences in human height PMID 36224396. The analysis included approximately 293 thousand participants and found a reported effect size of 0.029 with a p-value of 1e-11 PMID 36224396. These findings reflect population-level patterns rather than individual predictions.

Reported associations

• Height: Carriers of the C allele show a reported effect size of 0.029 for height variation, with statistical significance at p=1e-11 across a cohort of about 293 thousand individuals PMID 36224396.

Evidence quality The available evidence comes from a single large-scale genome-wide association study involving roughly 293 thousand participants PMID 36224396. The reported effect size of 0.029 reached strong statistical significance at p=1e-11, which is typical for well-powered height studies. Because only one dataset is currently provided, independent replication across diverse populations would strengthen confidence in this specific locus. The finding describes a common genetic correlation and does not imply a causal mechanism or clinical diagnosis.

Lifestyle considerations No lifestyle considerations on file for this variant.