rs10733356 - ADAMTSL1

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population - Unknown journal (n.d.) · Unknown authors · PubMed 32902719

  ABSTRACT: While the Arabian population has a high prevalence of metabolic disorders, it has not been included in global studies that identify genetic risk loci for metabolic traits. Determining the transferability of such largely Euro-centric established risk loci is essential to transfer the research tools/resources, and drug targets generated by global studies to a broad range of ethnic populations. Further, consideration of populations such as Arabs, that are characterized by consanguinity and a high level of inbreeding, can lead to identification of novel risk loci. We imputed published GWAS data from two Kuwaiti Arab cohorts (n = 1434 and 1298) to the 1000 Genomes Project haplotypes and performed meta-analysis for associations with 13 metabolic traits. We compared the observed ass

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