rs10733356 (ADAMTSL1): higher systolic blood pressure
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- rs10733356 is linked to higher systolic blood pressure
- effect size reported as 4.93 p=8e-7 in about 2 thousand individuals
- this common variant may not affect rare disease risk
Key takeaways
- rs10733356 is linked to higher systolic blood pressure
- effect size reported as 4.93 p=8e-7 in about 2 thousand individuals
- this common variant may not affect rare disease risk
What the research says This variant is associated with higher systolic blood pressure PMID 32902719. The reported effect size is 4.93 p=8e-7 in about 2 thousand individuals PMID 32902719.
Reported associations Systolic blood pressure - this variant is associated with higher systolic blood pressure a reported effect size of 4.93 p=8e-7 in about 2 thousand individuals PMID 32902719.
Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS catalog association with systolic blood pressure [PMID 32902719]. The effect size is small p=8e-7 sample size about 2 thousand individuals. No replication data provided.
Lifestyle considerations
- Alcohol (lifestyle, limit): carriers tend to have higher weekly intake
Frequently asked questions
What does rs10733356 mean?
It is a single nucleotide change in the ADAMTSL1 gene that has been associated with higher systolic blood pressure.
Is this variant linked to hypertension?
Yes it is associated with higher blood pressure values but not with other forms of hypertension.
Can I reduce my risk?
The evidence does not suggest a way to change the effect; lifestyle changes may help manage blood pressure.