rs10106920 - CSMD1

Magnitude 4.5 · 1 study on file

Reported associations

• Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis - Unknown journal (n.d.) · Unknown authors · PubMed 38630618

  ABSTRACT: Abstract Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise mechanisms for such influences are still unclear. A large-scale study investigating the host genetics of EBV serology and related clinical manifestations, such as infectious mononucleosis (IM), may help us better understand the role of EBV in MS pathogenesis. This study evaluates the host genetic factors that influence serological response against EBV and history of IM and cross-evaluates them with MS risk and genetic susceptibility in the Swedish population. Plasma IgG antibody levels against EBV nuclear antigen-1 [EBNA-1, truncated = amino acids (aa) (325-641), peptide = aa(385-420)] and vir

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