rs12419742 - OPCML

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide association study identifies susceptibility loci in IL6, RPS9/LILRB3, and an intergenic locus on chromosome 21q22 in Takayasu's arteritis - Unknown journal (n.d.) · Unknown authors · PubMed 25604533

  ABSTRACT: Objective Takayasu's arteritis is a rare large vessel vasculitis with incompletely understood etiology. We performed the first unbiased genome-wide association study (GWAS) in Takayasu's arteritis. Methods Two independent Takayasu's arteritis cohorts from Turkey and North America were included in our study. The Turkish cohort consisted of 559 patients and 489 controls, and the North American cohort consisted of 134 European-derived patients and 1,047 controls. Genotyping was performed using the Omni1-Quad and Omni2.5 genotyping arrays. Genotyping data were subjected to rigorous quality control measures and subsequently analyzed to discover genetic susceptibility loci for Takayasu's arteritis. Results We identified genetic susceptibility loci for Takayasu's arteritis wit

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