rs12376680 (PTPRD): gut microbiome abundance

Key takeaways

  • This SNP is linked to gut microbiome abundance.
  • The effect size is 1.59 with p=3e-8 in about 693 individuals.
  • The association involves Bifidobacterium longum and exclusive breastfeeding.

Key takeaways This SNP is linked to gut microbiome abundance. The effect size is 1.59 with p=3e-8 in about 693 individuals. The association involves Bifidobacterium longum and exclusive breastfeeding.

What the research says This variant is associated with gut microbiome abundance (class Bifidobacterium longum at 3 months x exclusive breastfeeding at 3 months interaction) [PMID 40187613]. The reported effect size is 1.59 with p=3e-8 in about 693 individuals [PMID 40187613].

Reported associations Gut microbiome abundance: This variant is associated with higher levels of Bifidobacterium longum at three months especially when combined with exclusive breastfeeding for three months [PMID 40187613].

Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog association. The study includes 693 individuals and reports an effect size of 1.59 with p=3e-8 [PMID 40187613].

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What does the rs12376680 SNP do?

It is linked to higher levels of a gut bacteria called Bifidobacterium longum especially when someone has been exclusively breastfed for three months.

Is this variant related to health conditions?

The research shows it affects gut microbiome composition but does not indicate any disease risk.

Can I change my diet because of this SNP?

There is no evidence that diet changes are needed; the link is observational only.