CSMD1 rs11984453 schizophrenia response
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to a higher Marder score in schizophrenia.
- The effect size is 1.81 with p=7e-6.
- It is associated with response to paliperidone.
Key takeaways This variant is linked to a higher Marder score in schizophrenia. The effect size is 1.81 with p=7e-6. It is associated with response to paliperidone.
What the research says This variant is associated with a higher Marder score in patients [PMID 27846195]. The effect size is 1.81 with p=7e-6 [PMID 27846195].
Reported associations Schizophrenia response to paliperidone: This variant is associated with a higher Marder score in patients [PMID 27846195] with an effect size of 1.81 and p=7e-6.
Evidence quality The GWAS used about 1000 individuals and reported a significant association with the variant G allele [PMID 27846195]. No replication studies are listed in this catalog entry.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs11984453 mean?
rs11984453 is a risk allele G that is linked to higher Marder scores in schizophrenia and better response to the antipsychotic paliperidone.
Is this variant common or rare?
The GWAS used about 1000 participants so the variant appears at moderate frequency but the association is significant with p=7e-6.
Can I take this information for treatment decisions?
No, this entry only describes a statistical link and does not recommend any medical action.