rs117927012 - LINGO2 linked to oligodendroglioma

Key takeaways

  • This SNP is linked to a brain tumor called oligodendroglioma.
  • The association was found in about 9 thousand people with a strong signal (p=1e-6).
  • It is not known to affect common health traits.

Key takeaways

  • This SNP is linked to a brain tumor called oligodendroglioma.
  • The association was found in about 9 thousand people with a strong signal (p=1e-6).
  • It is not known to affect common health traits.

What the research says This variant is associated with Oligodendroglioma, reported effect size 5.76, p=1e-6, in about 9 thousand individuals PMID 36810956.

Reported associations Oligodendroglioma (brain tumor) - the variant is linked to this condition with a reported effect size of 5.76, p=1e-6, based on about 9 thousand people [PMID 36810956].

Evidence quality The GWAS catalog entry reports an association in roughly 9 thousand individuals with a p-value of 1e-6 and no replication data provided. No conflicting findings are reported. Last lifestyle considerations on file for this variant.

Frequently asked questions

What does the rs117927012 variant do?

It is a genetic change in the LINGO2 gene that has been linked to oligodendroglioma based on a GWAS study with p=1e-6 and about 9 thousand participants.

Is this SNP related to common health conditions?

The evidence only shows an association with brain tumor; no link to other common traits is reported.

How strong is the genetic signal for rs117927012?

The study reports a p-value of 1e-6 in roughly 9 thousand people, indicating a very strong association.