rs117618210 (DLG2): bone mineral density and urate link
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is associated with lower femur bone mineral density
- The effect size is 1.69 with a very low p-value of 8e-9
- It also influences serum urate levels
Key takeaways
- This variant is associated with lower femur bone mineral density
- The effect size is 1.69 with a very low p-value of 8e-9
- It also influences serum urate levels
What the research says The GWAS found a link between this variant and changes in femur bone mineral density PMID 34046847. It also affects serum urate levels PMID 34046847.
Reported associations
- Femur bone mineral density: the variant is linked to lower levels of this trait a reported effect size of 1.69 p=8e-9 PMID 34046847
- Serum urate: the variant is linked to higher levels of this trait a reported effect size of 1.69 p=8e-9 PMID 34046847
Evidence quality The GWAS used about 4000 participants and reported a very strong association with both traits PMID 34046847. The evidence is limited to this single study.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs117618210 mean?
It is a DNA change in the DLG2 gene that has been linked to lower bone mineral density and higher uric acid levels.
Is this variant dangerous?
The study shows an association with these traits but does not indicate any health risk or disease.
Can I test for this variant?
Yes it is included in many genetic tests that report bone mineral density and uric acid results.