PTPRN2 rs117114682 breast cancer link
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to breast cancer in childhood survivors.
- The G allele increases risk with an effect size of 2.23 and p=4e-7.
- Only this association has been reported.
Key takeaways
- This variant is linked to breast cancer in childhood survivors with a reported effect size of 2.23 and p=4e-7 based on about 2000 individuals.
- The G allele is associated with higher risk.
What the research says This variant is associated with breast cancer in childhood cancer survivors 29059430. The G allele increases risk with an effect size of 2.23 and p=4e-7 [29059430].
Reported associations Breast cancer in childhood survivors this variant increases risk with an effect size of 2.23 and p=4e-7 [29059430].
Evidence quality The GWAS used about 2000 childhood cancer survivors and found the G allele associated with breast cancer (effect size 2.23, p=4e-7). This is a single association; no conflicting data reported.
No lifestyle considerations on file for this variant.
Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Screening
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breast cancer risk screening and assessment Moderate
PTPRN2 rs117114682 G-allele carriers show 2.23-fold increased breast cancer risk in cancer survivors
Discuss with oncologist or primary care physician about baseline screening age and frequency
Frequently asked questions
What does rs117114682 mean?
rs117114682 is a genetic change in the PTPRN2 gene that is linked to higher risk of breast cancer in childhood survivors.
Is this variant common?
The G allele is found at low frequency and has been studied in about 2000 individuals.
Can I reduce my risk with lifestyle changes?
_No lifestyle considerations on file for this variant._