rs11670527 - DUXA - ZNF264

Magnitude 2.0 · 1 study on file

Reported associations

• rs11670527 Upstream of ZNF264 Associated with Body Mass Index in the Coriell Personalized Medicine Collaborative. - Military medicine (2020) · Kusic DM, Roberts WN, Jarvis JP, Zhang P, Scheinfeldt LB, Rajula KD, Brenner R, Dempsey MP, Zajic SC · PubMed 31498392

  the effects of obesity on health are a concern for the military as they affect the fitness to serve of active service members, increase costs to the Military Health System, and reduce quality of life for veterans and beneficiaries. Although obesity can be influenced by behavioral and environmental factors, it has also been shown to be associated with genetic risk factors that are not fully understood. we performed a genome-wide association study of 5,251 participants in the Coriell Personalized Medicine Collaborative, which includes 2,111 Air Force participants. We applied a generalized linear model, using principal component analysis to account for population structure, and analyzed single-variant associations with body mass index (BMI) as a continuous variable, using a Bonferroni-correct

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