rs116124269 - DAB1 anxiety self-harm link
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to higher risk of anxiety and self-harm when birth by caesarian section is present
- The association is modest with a reported effect size of 0.07 p=3.2e-8 in about 300 people
- It does not cause disease on its own
Key takeaways
- This variant is linked to higher risk of anxiety and self-harm when birth by caesarian section is present
- The association is modest with a reported effect size of 0.07 p=3.2e-8 in about 300 people
- It does not cause disease on its own
What the research says This variant is associated with higher risk of anxiety and self-harm when birth by caesarian section is present [PMID 37029353]. The GWEIS identified DAB1 as a gene that interacts with birth by caesarian section for these traits [PMID 37029353].
Reported associations
- Anxiety - the variant is associated with a modest increase in risk (p=3.2e-8) [PMID 37029353].
- Self-harm - the variant is associated with a modest increase in risk (p=3.2e-8) [PMID 37029353].
Evidence quality The study used the UK Biobank cohort (n≈300) and reported a significant association with p=3.2e-8. No replication studies are available in the supplied data.
Last lifestyle considerations on file for this variant.
Frequently asked questions
What does the DAB1 gene do?
The DAB1 gene is a protein that can influence mental health traits such as anxiety and self-harm when combined with birth by caesarian section.
Is rs116124269 linked to anxiety?
Yes, the variant is associated with a modest increase in risk of anxiety when birth by caesarian section is present.
Can this variant cause disease on its own?
No, the variant does not cause disease on its own; it only shows an association under specific environmental conditions.