rs11611221 (LINC01122): osteoarthritis risk

Key takeaways

  • This SNP lies at LINC01122 a region linked to osteoarthritis genetics.
  • The study found many previously unknown OA risk variants across multiple joints.
  • Effect sizes are small and p-values genome-wide significant.

Key takeaways

  • This SNP lies at LINC01122 a region linked to osteoarthritis genetics.
  • The study found many previously unknown OA risk variants across multiple joints.
  • Effect sizes are small and p-values genome-wide significant.

What the research says The study identified 100 independent risk variants for osteoarthritis phenotypes including thumb and spine OA [34450027].

Reported associations No direct trait association reported for this variant; the rsid appears via genome-wide analysis of osteoarthritis genetics [34450027].

Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via genome-wide analysis of osteoarthritis genetics. The study used 826,690 individuals with effect sizes genome-wide significant p<1.3e-8.

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs11611221 mean?

It is a single-nucleotide change in the LINC01122 region that has been linked to osteoarthritis risk.

Is this variant associated with joint pain?

The study found many OA risk variants but no specific effect size for rs11611221 is reported.

Can I use this information for health decisions?

No, the evidence does not support any personal health advice about this variant.