rs116041786 - HLA-DQA1 protective for IgA deficiency
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Key takeaways
- This variant is protective for selective IgA deficiency.
- It lies 2.7kb upstream of HLA-DQA1 and has a p-value of 3.3e-92.
- No lifestyle considerations are linked to this variant.
Key takeaways
- This variant is protective for selective IgA deficiency.
- It lies 2.7kb upstream of HLA-DQA1 and has a p-value of 3.3e-92.
- No lifestyle considerations are linked to this variant.
What the research says The variant is protective for selective IgA deficiency (p = 3.3e-92) [PMID 27723758]. It lies 2.7kb upstream of the HLA-DQA1 gene and was identified as one of four new IgAD loci [PMID 27723758].
Reported associations Selective IgA deficiency: The variant is protective for selective IgA deficiency (p = 3.3e-92) [PMID 27723758].
Evidence quality The evidence comes from a genome-wide association study of 1,635 IgAD cases and 4,852 controls [PMID 27723758]. The variant shows a very low p-value indicating strong protection. There are no conflicting findings in the supplied data.
No lifestyle considerations on file for this variant.
Frequently asked questions
What does the rs116041786 variant do?
It is a protective allele for selective IgA deficiency with a very low p-value.
Is this variant linked to other diseases?
The study only links it to selective IgA deficiency; there are no known connections to other conditions.
Can I change my diet because of this variant?
No, the evidence does not suggest any dietary changes for this variant.