rs11545686 HLA-DQA1: allergen sensitization

Key takeaways

  • This variant is linked to higher risk of Hevea brasiliensis 8 sensitization with a small effect size.
  • The association was found in about 564 people with p=4e-8.
  • The risk allele is C.

Key takeaways

  • This variant is linked to higher risk of Hevea brasiliensis 8 sensitization with a small effect size.
  • The association was found in about 564 people with p=4e-8.
  • The risk allele is C.

What the research says This variant is associated with allergen component sensitization (Hevea brasiliensis 8) with a reported effect size of 5.52 and p=4e-8 in about 564 individuals, where the risk allele is C [PMID 37780799].

Reported associations Allergen component sensitization this variant is associated with a higher risk of sensitization to Hevea brasiliensis 8 with an effect size of 5.52 and p=4e-8 [PMID 37780799].

Evidence quality The evidence comes from a GWAS catalog association in 564 individuals reporting an effect size of 5.52 and p=4e-8 [PMID 37780799] No replication data provided.

No lifestyle considerations on file for this variant.

Frequently asked questions

What does the rs11545686 HLA-DQA1 variant do?

It is associated with higher risk of sensitization to Hevea brasiliensis 8 a small effect size.

Is this variant linked to allergies?

Yes it is linked to increased risk of sensitization to the plant Hevea brasiliensis 8.

Can I change my risk by lifestyle?

No lifestyle considerations are on file for this variant.