rs112550385 (SSC5D-SBK2): Genomic Variant Overview
Key takeaways
- rs112550385 is located in the genomic region near two genes: SSC5D and SBK2.
- This variant was analyzed in a genome-wide association study of over 405,000 UK Biobank participants examining 129 traits.
- No specific trait associations or effect sizes for this variant are described in the available research.
- Evidence quality for this specific variant cannot be determined from the provided source alone.
Key takeaways
- rs112550385 is a genetic variant located in the genomic region near two neighboring genes, SSC5D and SBK2.
- This variant was analyzed as part of a large genome-wide association study of 405,088 UK Biobank participants examining 13.3 million variants across 129 traits.
- The available study describes the computational method used to detect associations but does not report specific findings for this variant in the provided text.
- No confirmed trait associations, effect sizes, or clinical annotations for rs112550385 can be established from the available source material.
- Evidence quality for this specific variant cannot be assessed from the provided study alone.
What the research says This variant was among 13.3 million genetic variants examined in a large-scale genome-wide association study of 405,088 UK Biobank participants, covering 79 quantitative traits and 50 disease traits using a computational method called Quickdraws. The available study text describes the overall performance and design of the Quickdraws method but does not enumerate specific association results, effect sizes, or p-values for rs112550385. No trait associations or functional annotations for this variant are described in the provided source material.
Reported associations
- No specific associations reported: The provided study analyzed this variant as part of a genome-wide scan but does not describe per-variant findings for rs112550385 in the available text. Specific association results for this locus are not detailed in the provided excerpt.
Evidence quality The sole study provided is a large-scale genome-wide association study applying the Quickdraws mixed-model method to 405,088 UK Biobank individuals across 13.3 million variants and 129 traits (79 quantitative, 50 disease). While the overall study design represents a well-powered sample, no specific data for rs112550385 appears in the available study text. Effect sizes, p-values, and replication status for this variant cannot be evaluated from the provided source. The provided study metadata does not include a PubMed ID, so no inline citation can be attached to these claims.
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What is rs112550385?
rs112550385 is a single-nucleotide polymorphism, meaning a single-letter difference in the DNA code, located near the SSC5D and SBK2 genes. It was analyzed as part of a large genome-wide association study of 405,088 UK Biobank participants examining 13.3 million variants.
What traits is rs112550385 associated with?
The available research does not report specific trait associations for rs112550385. It was included in a scan of 13.3 million variants across 79 quantitative and 50 disease traits, but per-variant results for this locus are not described in the available study text.
What are the SSC5D and SBK2 genes?
SSC5D and SBK2 are neighboring genes in the human genome near the location of rs112550385. The available research does not describe their specific biological functions or roles in relation to this variant.
How was rs112550385 studied?
This variant was included in a genome-wide association study of 405,088 UK Biobank participants that analyzed 13.3 million variants using a method called Quickdraws, which applies machine learning techniques to detect associations between genetic variants and traits at large scale.
Is rs112550385 linked to any disease?
No disease associations for rs112550385 are described in the available study text. The study in which it was analyzed examined 50 disease traits, but specific results for this variant are not reported in the provided source material.