Expressive

rs11165354 (TGFBR3): Genetic Variant Overview

Key takeaways

  • rs11165354 is located at the TGFBR3 gene locus.
  • No specific trait or disease associations for this variant were found in the provided study data.
  • No lifestyle or drug response annotations for this variant appear in the source material.

Key takeaways

  • No specific associations for rs11165354 were reported in the provided study data.
  • The single provided study focused on a distinct locus (TMEM163 at chromosome region 2q21) in the context of type 2 diabetes risk in an Indian population, and does not reference rs11165354 or TGFBR3.
  • No drug response, lifestyle, or clinical annotation data for this variant appears in the provided source material.

What the research says The single study provided is a two-stage genome-wide association study (GWAS, meaning a large systematic scan of genetic variants across the genome) of type 2 diabetes conducted in 12,535 people of Indian ethnicity. The study identified a new susceptibility locus at chromosome region 2q21, with the strongest signal residing within the gene TMEM163, not at the TGFBR3 locus. No data for rs11165354 or TGFBR3 appears anywhere in the provided source text.

Reported associations

  • No associations for rs11165354 were identified in the provided studies.

Evidence quality The provided source material contains no data for rs11165354 or the TGFBR3 locus. No evaluation of sample size, replication status, p-values, or effect sizes for this variant is possible from the available text.

Lifestyle considerations No lifestyle considerations on file for this variant.

Frequently asked questions

What is rs11165354?

rs11165354 is a single nucleotide polymorphism (a one-letter change in the DNA sequence) at the TGFBR3 gene locus. No specific trait or disease associations for this variant were present in the available study data.

Is rs11165354 linked to any disease or trait?

No disease or trait associations for rs11165354 were found in the provided study data.

What is TGFBR3?

TGFBR3 is a gene. The provided study data does not include information describing its function or any findings about the rs11165354 variant within it.