FAF1 rs111253797: edge-level brain connectivity
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Key takeaways
- Higher edge-level brain connectivity is linked to the variant.
- Slightly better peak expiratory flow also appears.
Key takeaways Higher edge-level brain connectivity is linked to the variant. Slightly better peak expiratory flow also appears.
What the research says This variant is associated with higher edge-level brain connectivity (effect size 6.1, p=1e-9) in about 30 thousand individuals PMID 36800424. It is also linked to peak expiratory flow (effect size 0.017, p=3e-21) in about 394 thousand individuals PMID 39789286.
Reported associations Edge-level brain connectivity: The variant is associated with higher edge-level brain connectivity, reported effect size 6.1 p=1e-9 in about 30 thousand individuals PMID 36800424. Peak expiratory flow: The variant is associated with peak expiratory flow, reported effect size 0.017 p=3e-21 in about 394 thousand individuals PMID 39789286.
Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog associations in PMID 36800424 and 39789286.
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs111253797 mean?
It is a DNA change in FAF1 that is linked to higher edge-level brain connectivity and slightly better lung function.
Is this variant dangerous?
No, the study shows only modest associations with health traits and no evidence of disease.
Can I test for it?
Yes, many genetic tests include FAF1 variants like rs111253797 in their analysis.