rs11077203 RBFOX1 neuroticism link

Key takeaways

  • This SNP is linked to neuroticism, a personality trait.
  • The effect size is small (6.5) with high significance (p=8e-11).
  • It affects the RBFOX1 gene which influences neuronal activity.

Key takeaways

  • This SNP is linked to neuroticism, a personality trait.
  • The effect size is small (6.5) with high significance (p=8e-11).
  • It affects the RBFOX1 gene which influences neuronal activity.

What the research says This variant is associated with neuroticism, a personality trait [PMID 29255261]. The effect size is 6.5 and p=8e-11 in about 329 thousand individuals.

Reported associations Neuroticism This variant increases neuroticism by a reported effect size of 6.5 p=8e-11 in about 329 thousand individuals [PMID 29255261].

Evidence quality The association is based on a GWAS of 329 thousand individuals with high significance p=8e-11. No conflicting findings reported. No lifestyle considerations on file for this variant.

Frequently asked questions

What does rs11077203 mean?

It is a genetic variant in the RBFOX1 gene that has been linked to neuroticism, a personality trait.

Is this SNP related to mental health?

The study shows an association with neuroticism but does not indicate any direct mental illness.

Can I change my risk?

No lifestyle changes are recommended for this variant; it is only associated with neuroticism.