rs10962594 - BNC2

Magnitude 4.5 · 1 study on file

Reported associations

• The Genetic Variations Associated With Time to Aseptic Loosening After Total Joint Arthroplasty. - The Journal of arthroplasty (2021) · Koks S, Wood DJ, Reimann E, Awiszus F, Lohmann CH, Bertrand J, Prans E, Maasalu K, Märtson A · PubMed 31791832

  Total joint arthroplasty (TJA) is one of the most frequent surgical procedures performed in modern hospitals, and aseptic loosening is the most common indication for revision surgeries. We conducted a systemic exploration of potential genetic determinants for early aseptic loosening. Data from 423 patients undergoing TJA were collected and analyzed. Three analytical groups were formed based on joint arthroplasty status. Group 1 were TJA patients without symptoms of aseptic loosening of at least 1 year, group 2 were patients with primary TJA, and group 3 were patients receiving revision surgery because of aseptic loosening. Genome-wide genotyping comparing genotype frequencies between patients with and without aseptic loosening (group 3 vs groups 1 and 2) was conducted. A case-control assoc

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