rs10962594 BNC2 and joint replacement risk
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to a higher risk of aseptic loosening after joint replacement with an effect size of 2.74 and p=7e-6 in about 386 people.
- The association is observed for the G allele which increases risk.
Key takeaways
- This variant is linked to a higher risk of aseptic loosening after joint replacement with an effect size of 2.74 and p=7e-6 in about 386 people.
- The association is observed for the G allele which increases risk.
What the research says This variant is associated with aseptic loosening after total joint arthroplasty PMID 31791832. The effect size reported is 2.74 and p=7e-6 in a sample of about 386 individuals.
Reported associations Aseptic loosening This variant increases the risk of aseptic loosening after joint replacement with an effect size of 2.74 and p=7e-6 PMID 31791832.
Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog association.
Frequently asked questions
What does rs10962594 mean?
rs10962594 is a genetic change in the BNC2 gene that has been linked to a higher chance of joint replacement loosening.
Is this variant common or rare?
The G allele is found at a modest frequency and the effect size is small indicating only a slight increase in risk.
Can I change my lifestyle to avoid this risk?
There are no specific lifestyle changes recommended for this SNP as it does not directly affect diet or behavior.