rs10924473 SMYD3 cognitive ability
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Key takeaways
- General cognitive ability is linked to this variant with a small effect size in about 300 thousand people.
- It increases expression only in testis tissue.
- No other traits are associated with this variant.
Key takeaways General cognitive ability is linked to this variant with a small effect size in about 300 thousand people. It increases expression only in testis tissue. No other traits are associated with this variant.
What the research says A genome-wide association study found the variant associated with general cognitive ability [29844566]. The variant increases expression in testis tissue according to GTEx data.
Reported associations
- General cognitive ability: the variant is associated with a small effect size of 4.67 p=3e-6 in about 300 thousand individuals [29844566].
Evidence quality The supplied study is a genome-wide association study of about 300 thousand individuals reporting the variant associated with general cognitive ability [29844566]. The effect size is small and p-value highly significant. There are no conflicting findings in this dataset.
Tissue-specific expression effects
- SMYD3: increased expression in testis tissue GTEx Portal.
Lifestyle considerations No lifestyle considerations on file for this variant.
Frequently asked questions
What does the SMYD3 gene do?
SMYD3 is a gene that controls how much of its protein is made in certain tissues like testis.
Is rs10924473 linked to general cognitive ability?
Yes the variant is associated with a small effect on general cognitive ability according to a genome-wide association study.