rs10766558 - NAV2: edge brain connectivity
Upload your raw genetic data once, we'll show you which variants you carry and what the research says.
Key takeaways
- This variant is linked to higher edge-level brain connectivity.
- The C allele may increase expression of the gene in testes.
- The association was found in a large GWAS of about 30 thousand individuals.
Key takeaways
- This variant is linked to higher edge-level brain connectivity.
- The C allele may increase expression of the gene in testes.
- The association was found in a large GWAS of about 30 thousand individuals.
What the research says This variant is associated with edge-level brain connectivity in a large GWAS of about 30 thousand individuals [PMID 36800424]. The C allele may increase expression of the gene in testes, as shown by GTEx data GTEx Portal.
Reported associations
- Edge-level brain connectivity: the C allele is associated with higher connectivity, reported effect size 8.2 p=2e-16 [PMID 36800424]
- Testis expression: the C allele increases gene expression in testes, slope +0.16 p=7.1e-8 GTEx Portal.
Evidence quality The supplied studies include a GWAS of 30 thousand individuals reporting an association with edge-level brain connectivity and a GTEx expression study showing increased testis expression; no conflicting findings are reported.
Tissue-specific expression effects
- GENE: increased expression in testes GTEx Portal.
Last lifestyle considerations on file for this variant.
Frequently asked questions
What does rs10766558 mean?
It is a common genetic variant that has been linked to higher edge-level brain connectivity and may increase expression of the gene in testes.
Is this SNP related to disease?
The evidence shows an association with brain connectivity but no direct disease link reported.
Can I change my diet because of this?
There are no lifestyle recommendations tied to this variant.