NAV2 rs10766557 brain connectivity SNP

Key takeaways

  • This variant is linked to brain connectivity
  • It shows increased expression in testes
  • The association is strong with a high p-value

Key takeaways

  • This variant is linked to brain connectivity
  • It shows increased expression in testes
  • The association is strong with a high p-value

What the research says This variant is associated with node-level brain connectivity in a genome-wide association study of about 30 thousand individuals, with an effect size of 6.12 and p=9e-10 PMID 36800424. It also shows increased expression in testes GTEx Portal.

Reported associations

  • Brain connectivity: the variant increases node-level connectivity with an effect size of 6.12 and p=9e-10 PMID 36800424. Evidence quality The supplied studies do not report a direct trait association for this variant; the rsid appears via GWAS Catalog PMID 36800424.

Tissue-specific expression effects

Lifestyle considerations on file for this variant.

Frequently asked questions

What does the NAV2 gene do?

NAV2 is a gene associated with variations that affect brain connectivity.

Is rs10766557 linked to osteoporosis?

No, the supplied studies do not report any association between this variant and bone health.

Does this SNP affect testosterone levels?

The evidence does not indicate a direct link to testosterone; only expression changes in testes are observed.