rs10762869 LNCAROD DKK1 protein levels
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Key takeaways
- LNCAROD is linked to DKK1 protein levels
- effect size 0.1 p=2e-33 in about 47 thousand individuals
- also linked to Dickkopf-1 levels with effect size 0.24 p=7e-19
Key takeaways LNCAROD is linked to DKK1 protein levels, effect size 0.1 p=2e-33 in about 47 thousand individuals, also linked to Dickkopf-1 levels with effect size 0.24 p=7e-19.
What the research says This variant is associated with DKK1 protein levels reported effect size 0.1 p=2e-33 in about 47 thousand individuals [PMID 39789286]. Another study links it to Dickkopf-1 levels with effect size 0.24 p=7e-19 in about 1 thousand individuals [PMID 34814699].
Reported associations DKK1 protein levels the T allele is linked to DKK1 protein levels with a reported effect size of 0.1 and p=2e-33 in about 47 thousand individuals [PMID 39789286]. Dickkopf-1 levels the variant is linked to Dickkopf-1 levels with a reported effect size of 0.24 and p=7e-19 in about 1 thousand individuals [PMID 34814699].
Evidence quality The evidence comes from two genome-wide association study catalog entries one reporting a small effect on DKK1 protein levels in 47 thousand individuals and another linking the variant to Dickkopf-1 levels in 1 thousand individuals [PMID 39789286][PMID 34814699]. No conflicting findings. No lifestyle considerations on file for this variant.
Frequently asked questions
What does the LNCAROD variant do?
It is linked to DKK1 protein levels with a small effect size p=2e-33 in about 47 thousand individuals. No known impact on health.
Is rs10762869 associated with Dickkopf-1?
Yes it is linked to Dickkopf-1 levels with an effect size of 0.24 and a very low p-value p=7e-19 in about 1 thousand people.
Can this variant affect my health?
The studies only show associations with protein levels not direct disease risk.