rs10087406 (PPP1R3B-DT): waist-hip index link
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Key takeaways
- This variant is linked to a small increase in waist-hip index
- It lowers protein production in the testis
- It raises protein production in the thyroid
Key takeaways
- This variant is linked to a small increase in waist-hip index
- It lowers protein production in the testis
- It raises protein production in the thyroid
What the research says This SNP is associated with waist-hip index 34021172.
Reported associations
- Waist-hip index: this SNP is linked to a small increase in waist-hip index (effect size 0.019 p=1e-9) 34021172
Evidence quality The GWAS involved about 186 thousand participants and found a strong association with waist-hip index [34021172].
Tissue-specific expression effects
- PPP1R3B: reduced expression in testis, whole blood, aorta, thyroid, esophagus, skin sun exposed lower leg, suprapubic region, basal ganglia, cerebellar hemisphere, caudate ganglion GTEx Portal
No lifestyle considerations on file for this variant.
Frequently asked questions
What does rs10087406 mean?
rs10087406 is a genetic variant that has been associated with a small increase in waist-hip index and affects expression of its gene.
Is this SNP related to thyroid disease?
The variant increases protein production in the thyroid but there is no evidence it causes disease.
Can I change my diet because of this?
There are no lifestyle recommendations tied to this variant.