rs12450323 - IKZF3

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype - Unknown journal (n.d.) · Unknown authors · PubMed 24388013

  ABSTRACT: Background To date, no genome-wide association study (GWAS) has considered the combined phenotype of asthma with hay fever. Previous analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma without hay fever. Objective We sought to perform a GWAS of asthma with hay fever to identify variants associated with having both diseases. Methods We performed a meta-analysis of GWASs comparing persons with both physician-diagnosed asthma and hay fever (n = 6,685) with persons with neither disease (n = 14,091). Results At genome-wide significance, we identified 11 independent variants associated with the risk of having asthma with hay fever, including 2 associations reaching this level of significance

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